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<b><span style="font-size:48.0pt;font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">NEWS RELEASE</span></b><span style="font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E"><o:p></o:p></span></p>
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<b><span style="font-size:10.0pt;font-family:"Avenir LT Std 55 Roman",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in"> </span></b><span style="font-family:"Avenir LT Std 55 Roman",sans-serif;color:#201F1E"><o:p></o:p></span></p>
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<b><span style="font-size:10.0pt;font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">For Immediate Release Date: 10/27/2021<o:p></o:p></span></b></p>
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<b><span style="font-size:10.0pt;font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">Contact: Public Information Office Phone: (919) 560-0000/Fax: (919) 560-0020</span></b><span style="font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E"><o:p></o:p></span></p>
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<b><span style="font-size:10.0pt;font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">E-mail: </span></b><span style="color:black"><a href="mailto:publicinformationoffice@dconc.gov" target="_blank"><span style="font-family:"Avenir Next LT Pro",sans-serif;border:none windowtext 1.0pt;padding:0in">publicinformationoffice@dconc.gov</span></a></span><span style="font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E"><o:p></o:p></span></p>
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<b><span style="font-size:16.0pt;font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">Jaguar Gene Therapy Selects Durham County for GMP Facility
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<span style="font-size:12.0pt;font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">Company’s $125M investment will create 250 new jobs<o:p></o:p></span></p>
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<b><span style="font-size:12.0pt;font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">Durham, N.C.
</span></b><span style="font-family:"Avenir Next LT Pro",sans-serif;border:none windowtext 1.0pt;padding:0in">– Durham expands its gene therapy cluster with North Carolina Governor Roy Cooper’s announcement on Tuesday, October 26, 2021, that
</span><a href="https://jaguargenetherapy.com/"><span style="font-size:12.0pt;line-height:106%;font-family:"Avenir Next LT Pro",sans-serif;border:none windowtext 1.0pt;padding:0in">Jaguar Gene Therapy</span></a><span style="font-family:"Avenir Next LT Pro",sans-serif;border:none windowtext 1.0pt;padding:0in">,
</span><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black;background:white">will locate a Good Manufacturing Practice (GMP) facility in Durham County. The company will invest $125 million and create 250 jobs over 8 years at the North Carolina
site.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;border:none windowtext 1.0pt;padding:0in"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black;background:white">“North Carolina’s diverse life sciences presence continues to attract innovative biopharmaceutical companies," said Governor Cooper in a
</span><a href="https://www.nccommerce.com/news/press-releases/governor-cooper-announces-jaguar-gene-therapy%E2%80%99s-plans-invest-125-million-and"><span style="font-size:12.0pt;line-height:106%;font-family:"Avenir Next LT Pro",sans-serif;background:white">release</span></a><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black;background:white">.
“Jaguar’s expansion into biomanufacturing in Research Triangle Park, together with its process sciences laboratory in Cary, reinforces North Carolina’s reputation as a premier location for these companies."<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;border:none windowtext 1.0pt;padding:0in"><o:p> </o:p></span></p>
<p class="MsoNormal"><a href="https://jaguargenetherapy.com/"><span style="font-size:12.0pt;line-height:106%;font-family:"Avenir Next LT Pro",sans-serif;background:white">Jaguar Gene Therapy</span></a><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black;background:white">,
based out of Lake Forest, Illinois, is focused on accelerating breakthroughs in gene therapy for larger patient populations suffering from severe genetic diseases and is led by experts in the development, manufacturing, and commercialization of novel gene
therapy treatments. Once fully converted to Jaguar’s gene therapy manufacturing specifications, the GMP facility in Research Triangle Park will support future clinical and commercial production of the company’s initial programs, including: galactosemia; a
specific genetic cause of autism; and Type 1 diabetes. The 174,000-square-foot facility is located approximately 20 miles from Jaguar’s existing Process Sciences Laboratory in Cary, expanding the company’s North Carolina presence.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><a name="_Hlk86148716"><span style="font-family:"Avenir Next LT Pro",sans-serif">“With the addition of Jaguar Gene Therapy to the Durham community, we welcome their pursuit of advanced treatments for severe genetic diseases,” said Durham
Board of County Commissioners Chair Brenda Howerton. “Supported by partnerships at the local, regional and state level, we have fostered an environment that maintains Durham County as a premiere location for investments in life sciences. Paired with workforce
development strategies to grow the local talent pipeline, we look forward to the opportunities that will benefit the broader community.”<o:p></o:p></span></a></p>
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<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black">This expansion by Jaguar Gene Therapy will be facilitated, in part, by a Job Development Investment Grant (JDIG) approved by the state’s Economic Investment Committee
earlier today. Over the course of the 12-year term of the grant, economists in the Department of Commerce estimate the project will grow the state’s economy by more than $279 million. The JDIG agreement authorizes the potential reimbursement to the company
of up to $2,355,000 spread over 12 years. P<span style="background:white">ayments for all JDIG and local awards are performance-based and only occur following verification that the company has met its incremental job creation and investment targets.
</span><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black;background:white">Because Jaguar Gene Therapy is expanding in Durham County, classified by the state’s economic tier system as Tier 3, the company’s JDIG agreement also
calls for moving as much as $785,000 into the state’s </span><a href="https://www.nccommerce.com/grants-incentives/public-infrastructure-funds/utility-account"><span style="font-family:"Avenir Next LT Pro",sans-serif">Industrial Development Fund – Utility
Account</span></a><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black;background:white">. The Utility Account helps rural communities finance necessary infrastructure upgrades to attract future business. Even when new jobs are created in a
Tier 3 county such as Durham, the new tax revenue generated through JDIG grants helps more economically challenged communities elsewhere in the state.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black">The Board of County Commissioners are scheduled to consider a local award at the Monday, November 8, 2021, Regular Session.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><a name="_Hlk72410953"><span style="font-family:"Avenir Next LT Pro",sans-serif;border:none windowtext 1.0pt;padding:0in">“With today’s announcement of Jaguar Gene Therapy expanding in the region, Durham is further establishing itself as
one of the premiere gene therapy clusters in the country and beyond,” stated Durham County Economic Development Officer Andrew Miracle. “By aiming to serve populations with large unmet need, Jaguar will be an excellent addition to the Research Triangle’s life
sciences industry. We look forward to this partnership opportunity.”<o:p></o:p></span></a></p>
<span style="mso-bookmark:_Hlk72410953"></span>
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<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black;background:white">In addition to the N.C. Department of Commerce and the Economic Development Partnership of North Carolina, other key partners in the project include
the North Carolina General Assembly, North Carolina Community College System, North Carolina Biotechnology Center, the Greater Durham Chamber of Commerce and Duke Energy.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black">For more information about this announcement, contact Economic Development Officer Andrew Miracle at
</span><a href="mailto:amiracle@dconc.gov"><span style="font-family:"Avenir Next LT Pro",sans-serif">amiracle@dconc.gov</span></a><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black">.<o:p></o:p></span></p>
<p style="margin:0in;line-height:150%"><span style="font-family:"Avenir Next LT Pro",sans-serif;color:black"><o:p> </o:p></span></p>
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<span style="font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">###</span><span style="font-family:"Avenir Next LT Pro",sans-serif;color:#201F1E"><o:p></o:p></span></p>
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